"Progressive Metabolic Acidosis or Bicarbonate Measurement Error?"
نویسندگان
چکیده
منابع مشابه
Bicarbonate therapy in severe metabolic acidosis.
The utility of bicarbonate administration to patients with severe metabolic acidosis remains controversial. Chronic bicarbonate replacement is obviously indicated for patients who continue to lose bicarbonate in the ambulatory setting, particularly patients with renal tubular acidosis syndromes or diarrhea. In patients with acute lactic acidosis and ketoacidosis, lactate and ketone bodies can b...
متن کاملComment on “Sodium Bicarbonate Therapy in Patients with Metabolic Acidosis”
Metabolic acidosis occurs when a relative accumulation of plasma anions in excess of cations reduces plasma pH. Replacement of sodium bicarbonate to patients with sodium bicarbonate loss due to diarrhea or renal proximal tubular acidosis is useful, but there is no definite evidence that sodium bicarbonate administration to patients with acute metabolic acidosis, including diabetic ketoacidosis,...
متن کاملAcute haemodynamic effect of sodium bicarbonate in canine respiratory or metabolic acidosis.
This study has examined the acute haemodynamic effects of 7% sodium bicarbonate solution 1 mmol kg-1 (1.2 ml kg-1) administered into the right atrium over 5 s in 25 anaesthetized dogs allocated randomly to respiratory (arterial pH (pHa) 7.18, PaCO2 10.1 kPa (n = 8)) or metabolic acidosis (pHa 7.27, base deficit -9.0 mmol litre-1 (n = 7)) or metabolic neutrality (pHa 7.39 (n = 10)). The pHa and ...
متن کاملLactic acidosis: high-dose or low-dose bicarbonate therapy?
occurs intracellularly, extracellularly, and in the cerebrospinal fluid (CSF). Adding sodium bicarbonate to the extracellular fluid causes a decrease in hydrogen ions with subsequent increase in carbon dioxide (CO2) concentration. Since CO2) but not bicarbonate, readily diffuses across cell membranes and into the CSF, this leads to an increase in intracellular and CSF CO2 concentration, with co...
متن کاملBicarbonate therapy and intracellular acidosis.
1. The correction of metabolic acidosis with sodium bicarbonate remains controversial. Experiments in vitro have suggested possible deleterious effects after alkalinization of the extracellular fluid. Disequilibrium of carbon dioxide and bicarbonate across cell membranes after alkali administration, leading to the phenomenon of 'paradoxical' intracellular acidosis, has been held responsible for...
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ژورنال
عنوان ژورنال: Clinical Pathology & Research Journal
سال: 2019
ISSN: 2642-6145
DOI: 10.23880/cprj-16000115